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Beschreiben sie kurz die molekularen Prozesse der Signaltransduktion olfaktorischer Sinneszellen. An welcher Stelle findet eine Signalverstärkung statt?
- 1000 different odorant genes
- Odorant sensory cell are 7 transmembrane domain proteins + G-protein
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disassociation of G-Protein complex
alpha segment binds to adenylyl cyclase cAMP production (level increase)
cAMP opens CNG channels Ca^{2+}-influx depolarization
- opening of Ca^{2+}-gated Cl-channels chloride efflux further depolarization
- amplification of other channels feed forward
- Odorant sensory cell are 7 transmembrane domain proteins + G-protein
-
disassociation of G-Protein complex alpha segment binds to adenylyl cyclase
cAMP production (level increase) cAMP opens CNG channels Ca^{2+}-influx depolarization - opening of Ca^{2+}-gated Cl-channels
chloride efflux further depolarization - amplification of other channels
feed forward 
Karteninfo:
Autor: szara
Oberthema: Biology
Thema: Neurobiology
Schule / Uni: University of Osnabrück
Ort: Osnabrück
Veröffentlicht: 06.04.2010