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How is Cholera Toxin exported? Explain the steps:
1.) CT-A and CT-B are synthesized as pro-peptides in the cytosol.
2.) During the transport through the plasma membrane by the sec pathway, the signal sequence is removed.
3.) CT-A and CT-B fold an assemble in the periplasma. Disulfid bridges are introduced by DsbA.
4.) The holotoxin is now transported across the outer membrane by Type 2 translocon
2.) During the transport through the plasma membrane by the sec pathway, the signal sequence is removed.
3.) CT-A and CT-B fold an assemble in the periplasma. Disulfid bridges are introduced by DsbA.
4.) The holotoxin is now transported across the outer membrane by Type 2 translocon
Karteninfo:
Autor: CoboCards-User
Oberthema: Bioloige
Thema: Mikorbiologie
Veröffentlicht: 14.06.2012