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8
Why don't we prescribe sleeping tablets in elderly?
Benzodiazepines accumulate due to
- reduced hepatic metabolism
- increased Vd
- reduced albumin bindings
ADRs
- hypothermia, increased dependence, increased sedation, hangover effects, confusion, ataxia, memory problems, unsteady gait and balance problems
- reduced hepatic metabolism
- increased Vd
- reduced albumin bindings
ADRs
- hypothermia, increased dependence, increased sedation, hangover effects, confusion, ataxia, memory problems, unsteady gait and balance problems
