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What are the effects of Glucocorticoids by tissue?
Metabolism | Liver, Fat, Muscle | Increased Glucose, Lipolysis, Muscle wasting |
Calcium | Kidney, bone, GI | Reduced absorption, collagen synthesis |
Immune | Cells | Inhibited |
Skin | Antiproliferative | causes easy bruising |
Breast | Epithelium | Galactorrhea |
CV system / Kidney | Heart, Vasculature, Kidney | Increased ECF, Contractility, Response to Constrictors |
Psychiatric | Mood, Sleep | Mood variable. Less REM, Increased Appetite |