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6
Sarcoplasmic Reticulum (SR)
Related to : membrane complex
Tightly bound to
Forms tubular network around each
Enlarge, fuse and form expanded chambers on either side of T-tubules =
Pair of + T-tubules =
actively pumped from sarcoplasm into of SR
Resting muscle
Sacroplasm: low [ ]
Related to : membrane complex
Tightly bound to
Forms tubular network around each
Enlarge, fuse and form expanded chambers on either side of T-tubules =
Pair of + T-tubules =
actively pumped from sarcoplasm into of SR
Resting muscle
Sacroplasm: low [ ]
Sarcoplasmic Reticulum (SR)
Related to SER: membrane complex
Tightly bound to T-tubules
Forms tubular network around each myofibril
Enlarge, fuse and form expanded chambers on either side of T-tubules = terminal cisternae
Pair of terminal cisternae + T-tubules = triad
Ca2+ actively pumped from sarcoplasm into terminal cisternae of SR
Resting muscle
Sacroplasm: low [Ca2+]
SR: 1000x free Ca2+ and 40000x free + bound Ca2+
AP leads to release of Ca2+ from SR into sarcoplasm
Ca2+ diffuses into individual contractile units
Related to SER: membrane complex
Tightly bound to T-tubules
Forms tubular network around each myofibril
Enlarge, fuse and form expanded chambers on either side of T-tubules = terminal cisternae
Pair of terminal cisternae + T-tubules = triad
Ca2+ actively pumped from sarcoplasm into terminal cisternae of SR
Resting muscle
Sacroplasm: low [Ca2+]
SR: 1000x free Ca2+ and 40000x free + bound Ca2+
AP leads to release of Ca2+ from SR into sarcoplasm
Ca2+ diffuses into individual contractile units
