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In a person with flank pain, the combination of the following symptoms suggests a kidney disorder:

• Pain over one or both kidneys (can be absent)
• In general, kidney pain is not aggravated by the body movements or deep inhalation
• Tenderness over one or both kidneys (can be absent)
• Urine changes: frequent urination, cloudy urine
• Nausea
• Fever

Two other main causes of flank pain:

• Muscle pain changes with the body movements.
• Pain from abdominal organs also usually appears in the abdomen.