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What is the funtion of the enzyme "sortase" ?
recognition and cleavage of the LPXTG motif of surface proteins and generation of a acyl enzyme intermediate, which after reacts with lipid II for PG-anchoring.
(After a nucleophilic attack of the free amino group of the pentapeptide from a precursor MurNAc-pentapeptide, the surface protein is incorporated into the cell wall.)
(After a nucleophilic attack of the free amino group of the pentapeptide from a precursor MurNAc-pentapeptide, the surface protein is incorporated into the cell wall.)
Karteninfo:
Autor: CoboCards-User
Oberthema: Bioloige
Thema: Mikorbiologie
Veröffentlicht: 14.06.2012