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7
How do you control for E2, versus SN2?
-bulky, stronger base
(NOT -CN or -I or even -OH, but -OR)
-substrate steric hindrance
(why?
hydrogen removal rather than 
)
-HEAT
Key Points
bulky base = E2
heat = E2
3*C substrate = E2
(NOT -CN or -I or even -OH, but -OR)
-substrate steric hindrance
(why?
hydrogen removal rather than )-HEAT
Key Points
bulky base = E2
heat = E2
3*C substrate = E2
