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● <140/90 mm Hg. The exceptions are patients with diabetes (<140/85 mm Hg) and less fit elderly (>65 years) patients (140-150/<90 mm Hg).
● Most likely there is a limit to the beneficial effects of a therapeutic blood pressure lowering ("J curve concept"), so do not overdo! Especially in the elderly too strong or rapid lowering of blood pressure may be deleterious. Starting therapy with a fraction of the target dose ("start low, go slow") in these patients is especially critical.
≣ Section 4.3