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What is progeria? What are its characteristics at genetic level?
What are the two types?
What are the two types?
- rare genetic disease in which individuals display accelerated ageing
- genes mutated in progeria are likely to be required for maintaining or repairing cells/tissue
1. unimodal progeroid syndrome - only a single tissue is affected e.g alzheimers disease
2. Segmental progeroid syndromes - multiple tissues affected but some features of ageing not observed
- genes mutated in progeria are likely to be required for maintaining or repairing cells/tissue
1. unimodal progeroid syndrome - only a single tissue is affected e.g alzheimers disease
2. Segmental progeroid syndromes - multiple tissues affected but some features of ageing not observed