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All main topics / Bioloige / Mikorbiologie / Molekulare Mikorbiologie
108
How is Cholera Toxin exported? Explain the steps:
1.) CT-A and CT-B are synthesized as pro-peptides in the cytosol.

2.) During the transport through the plasma membrane by the sec pathway, the signal sequence is removed.

3.) CT-A and CT-B fold an assemble in the periplasma. Disulfid bridges are introduced by DsbA.

4.) The holotoxin is now transported across the outer membrane by Type 2 translocon
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Flashcard info:
Author: CoboCards-User
Main topic: Bioloige
Topic: Mikorbiologie
Published: 14.06.2012

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