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Norm is greater than one. anything less than one is indicator of disease.

If liver malfunctions Alb goes down, but total unaffected.

Hyperproteinemia-lots of protein in blood stream
causes: dehydration (proportionate decrease in all fractions
or multiple myeloma-increases in one clone of Ig but alb does not change->low alb/glu

Hypoproteinemia-
decrease protein in blood
alb/glb ratio decreased

decreased intake-malnutrition or malabsorption-=-> no change or decrease in ratio