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17
Rheumatoid Arthritis:
What are the effectors that mediate the disease? How frequent.? What is Rheumatoid Factor?
What are the effectors that mediate the disease? How frequent.? What is Rheumatoid Factor?
Effectors:
T cells, B cells, Macrophages & Neutrophils
Prostaglandins / Leukotrienes mediate inflammation
Lysosomal enzymes, proteinases, collagenases, TNF
, IL-1, 8.
1-3% of the US.
80% have Anti-Antibodies called rheumatoid factor
Fc portion of human IgG
T cells, B cells, Macrophages & Neutrophils
Prostaglandins / Leukotrienes mediate inflammation
Lysosomal enzymes, proteinases, collagenases, TNF
, IL-1, 8.1-3% of the US.
80% have Anti-Antibodies called rheumatoid factor
Fc portion of human IgG
