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13
medulloblastoma
invasive
mitotically active
aggressive
WHO grade IV
midline of midbrain
hypercellular
primitive (embryonal) cells with neuronal features
Homer-Wright rosettes
peripheral pallisade of nuclei around acellular zone
chemosensitive => good survival
frequently seeds CSF
drop metastases
mitotically active
aggressive
WHO grade IV
midline of midbrain
hypercellular
primitive (embryonal) cells with neuronal features
Homer-Wright rosettes
peripheral pallisade of nuclei around acellular zone
chemosensitive => good survival
frequently seeds CSF
drop metastases