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Why are ACh-esterase inhibitors like neostigmine helpful?
•Muscle function is improved by cholinesterase inhibitors, such as neostigmine and pyridostigmine.
•These slow the natural enzyme cholinesterase that degrades acetylcholine in the motor end plate;
•The neurotransmitter is therefore around longer to stimulate its receptors (which there are less of in this disease).
•These slow the natural enzyme cholinesterase that degrades acetylcholine in the motor end plate;
•The neurotransmitter is therefore around longer to stimulate its receptors (which there are less of in this disease).
