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Tell me everything about first generation Sulfonylureas (names, mechanism, side effects)

tolbutamide, tolazamide, acetohexamide, chlorpropamide

inhibit ATP/K+ channels

SEVERE PROTRACTED HYPOGLYCEMIA THAT KILLS
WEIGHT GAIN

Tags: diabetes, drug classes, endo, pharmacology, type 2 diabetes
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School / Univ.: MSUCOM

Published: 10.03.2010