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what happens if leptin in blood is decreased, how does the homeostatic metabolic thing react?
- Decrease leptin turn off αMSH & CART responses
-results in activation of sub group neurones in ARH that contain neuropeptides
neuropeptide Y (NPY)
agouti-related peptide (AgRP)
These neurones connected PVN & LHA
-NPY & AgRP inhibit TSH & ACTH secretion (decrease vicero-motor response)
-Activate parasympathetic nervous system (inhibit sympathetic nervous system)
-Stimulate feeding behaviour via LHA
- LHA neurones contain melanin-concentrating hormone (MCH) and orexin neurons which initiate feeding behavior
-results in activation of sub group neurones in ARH that contain neuropeptides
neuropeptide Y (NPY)
agouti-related peptide (AgRP)
These neurones connected PVN & LHA
-NPY & AgRP inhibit TSH & ACTH secretion (decrease vicero-motor response)
-Activate parasympathetic nervous system (inhibit sympathetic nervous system)
-Stimulate feeding behaviour via LHA
- LHA neurones contain melanin-concentrating hormone (MCH) and orexin neurons which initiate feeding behavior
