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177
what is a glutamate receptor?
what are the agonists and antagonists?
what are the agonists and antagonists?
-Glutamate receptors are synaptic receptors located primarily on the membranes of neuronal cells
-Glutamate receptors are responsible for the glutamate-mediated post-synaptic excitation of neural cells
ionotropic agonists (Ligand-gated ion channels (LGICs) are one type of ionotropic receptor or channel-linked receptor. They are a group of transmembrane ion channels that are opened or closed in response to the binding of a chemical messenger such as a neurotransmitter)
- AMPA(kainate) (opens for the n and k channels)
- NMDA(opens for the na k and ca channels)
antagonists
AP5
CNQX
-Glutamate receptors are responsible for the glutamate-mediated post-synaptic excitation of neural cells
ionotropic agonists (Ligand-gated ion channels (LGICs) are one type of ionotropic receptor or channel-linked receptor. They are a group of transmembrane ion channels that are opened or closed in response to the binding of a chemical messenger such as a neurotransmitter)
- AMPA(kainate) (opens for the n and k channels)
- NMDA(opens for the na k and ca channels)
antagonists
AP5
CNQX
